Impact of phosphamidon and its metabolites on histopathology of the liver, gill and intestine of Labeo rohita

Impact of phosphamidon, an organophosphorus pesticide and its metabolites viz. dimethyl phosphoric acid and 2-chloro 2-diethyl carbamoylmethyl vinyl acid on histopathology of a common teleost, Labeo rohita was studied by exposing the fish to sub-lethal concentrations which were taken as 1/3rd of LC50 and were equal to 0.0123 ppm for phosphamidon, 0.0160 ppm for dimethyl phosphoric acid and 0.0167 ppm for 2-chloro 2-diethyl carbamoylmethyl vinyl acid respectively. The results revealed that hepatocytes in the liver were markedly swollen and exhibited hydropic degeneration. Fusion of primary lamellae and moderate congestion of blood vessels were evident in the gill. Intestine showed degeneration of mucosa and cellular infiltration in sub-mucosa. LC50 values and histopathological photomicrographs suggest that phosphamidon is more toxic as compared to dimethyl phosphoric and 2-chloro 2-diethyl carbamoylmethyl vinyl acid

Copper, zinc, iron and manganese in sediments and in the rock oyster Saccostrea cucullata in Mumbai coast

Sediment and oyster (Saccostrea cucullata) samples were collected at Dhanda, a fishing village in Mumbai, Maharashtra. The samples were analysed for copper, zinc, iron and manganese contents. Metal concentrations in the sediments and bioaccumulated levels in oysters were correlated. There is no positive correlation between the total sedimentary levels of metals analysed and the bioaccumulated levels of respective metals in oyster. A positive correlation between the bioavailable fractions of zinc, iron and manganese, and the bioaccumulated levels exists. Copper, however, shows a negative correlation with respect to the bioaccumulated levels

Achieving Circularity is a Distant Dream: Entrepreneurial Barriers to Circular Business Models in SMEs of Emerging Economies

Purpose: Circularity has acted as an essential phenomenon for Small and Medium Enterprises (SMEs) in emerging economies, pressuring entrepreneurs to its adoption in their businesses. During the adoption and implementation of circularity, entrepreneurs or circular entrepreneurs (to be precise) are facing various challenges to its effective functioning. However, the scholarly literature has offered limited research into this phenomenon. Thus, the purpose of this research is to identify the various barriers and sub-barriers for circular entrepreneurs to adopt circularity in SMEs of emerging economies. Design/methodology/approach: A combined qualitative and quantitative approach was employed to achieve the objectives of the study. In the first stage, through an extensive literature review, a list of barriers was identified and in the second stage, a deductive approach was employed to finalize the barriers. Finally, Best-Worst Method (BWM), a multi-criteria decision-making (MCDM) method, was used to analyze the significant importance of the barriers. Findings: The findings of the study suggested the ‘financial barrier’ as the first-ranked barrier in the adoption of Circular Business Models (CBMs), followed by the ‘regulatory and operational barriers’ as the top second and third barriers. In terms of sub-barriers, ‘lack of access to funding and capital’ has been identified as the top sub-barrier in the adoption of CBM, followed by ‘excessive regulations and red tape’ and ‘challenges due to ambiguity of the concept’. Practical implications: To transition from a circular to a linear business approach considerably quicker and smoother, entrepreneurs may utilize the findings of this study as a blueprint for the steps to overcome the barriers in a linear to a circular transition. Originality: This research differentiates from other studies due it solicited input directly from the people who are most familiar with the challenges of making the transition from linear to CBM, i.e. the entrepreneurs themselves

Deltamethrin induced alterations of hematological and biochemical parameters in fingerlings of Catla catla (Ham.) and their amelioration by dietary supplement of vitamin C

The present study was carried out to investigate the sub-lethal toxicity of technical grade deltamethrin (a synthetic pyrethroid) of concentration 1.61 μg/L (1/3rd of 96 h LC50) on hematological and biochemical parameters of catla (Catla catla) fingerlings and its amelioration through dietary vitamin C. The deltamethrin exposed fishes were fed with different levels of supplemented vitamin C such as 50, 250, 500 and 1000 mg/kg diet to see its ameliorating effect by assaying hematological parameters viz. total erythrocyte count (TEC), total leukocyte count (TLC), hemoglobin content (Hb), total serum protein, albumin, globulin, albumin–globulin ratio and biochemical parameters such as lactate dehydrogenase (LDH), acetylcholine esterase (AChE), alanine amino transferase (ALT), aspartate amino transferase (AST), total adenosine triphosphatase (ATPase), magnesium adenosine triphosphatase (Mg2+-ATPase) and sodium potassium adenosine triphosphatase (Na+, K+-ATPase) activities. The finding of this study showed that deltamethrin had negative effect on the hematological and biochemical parameters of Catla catla. The experimental group, which was exposed to deltamethrin and fed with normal diet showed significantly lower values (P ⩽ 0.05) of all parameters studied except ALT activity. This might be due to possible disruption of hematopoiesis and proteosynthesis. However, the fish fed with varied concentration of vitamin C in diets neutralized the toxic effect of deltamethrin, as evidenced by significantly lowered hematological and biochemical response. Vitamin C @ 1000 mg/kg diet was the most effective in amelioration of harmful effect of deltamethrin on hematological and biochemical parameters of catla fingerlings. The result suggests that vitamin C can be effectively used to neutralize the toxic effect of deltamethrin on catla

Grain boundaries in granular materials-A fundamental limit for thermal stability

This is the final version of the article. Available from the American Institute of Physics via the DOI in this record.We show that thermal-stability and the associated switching field in well segregated, nanoscale granular materials is explained by grain boundary and interface effects. Grain boundaries pose a fundamental limit on scaling rooted in their chemical and morphological structure, while exchange interactions across interfaces cause the switching to deviate from the expected coherent Stoner-Wohlfarth behaviour. Measurements and simulations of CoCrPt-systems show a clear shift in applied field angle behaviour, arising from exchange-coupling between magnetic-phases, while the quantitative switching field can only be explained by a transition layer surrounding the grains. These results are potentially significant for Heat-Assisted-Magnetic Recording and Bit-Patterned-Media Recording. © 2013 AIP Publishing LLC.We would like to thank the EPSRC for financial support under Grants No. EP/G032440/1, EP/G032300/1, the WWTF Project MA09-029 and the Royal Society

Alteration in haematological and biochemical parameters of Catla catla exposed to sub-lethal concentration of cypermethrin

A 60-day experiment was carried out to study the effect of sub-lethal concentration of cypermethrin (1/10th of LC50) exposure on haematological and biochemical parameters of the Indian major carp, Catla catla fingerlings. Under exposure, the total erythrocyte count, total leucocyte count, haemoglobin content and haematocrit were decreased. All the studied serum parameters viz. total serum protein, albumin, globulin contents and albumin–globulin ratio were significantly decreased in cypermethrin-exposed fishes. A marked increase was recorded in alanine aminotransferase and aspartate aminotransferase activities in liver, whereas lactate dehydrogenase activity of muscle and acetylcholine esterase activity in brain were inhibited in cypermethrin-exposed fish. The membrane transport enzymes (total adenosine triphosphatase, sodium–potassium adenosine triphosphatase and magnesium adenosine triphosphatase) activities were decreased significantly in the gills of C. catla exposed to sub-lethal concentration of cypermethrin. The present study indicates that sub-lethal exposure of C. catla fingerlings to cypermethrin alters the haematological and biochemical parameters

CLASSIFICATION AND ASSESSMENT OF THE LAND USE – LAND COVER CHANGES IN JODHPUR CITY USING REMOTE SENSING TECHNOLOGIES

Land Use – Land Cover (LULC) classification mapping is an important tool for management of natural resources of an area. The remote sensing technology in recent times has been used in monitoring the changing patterns of land use-land cover. The aim of the study is to monitor the LULC changes in Jodhpur city over the period 1990–2018. Satellite imagery of Landsat 8 OLI (June, 2018) & Landsat TM (Oct, 1990) were used for classification analysis. Supervised classification-maximum likelihood algorithm is used in ENVI software to detect land use land cover changes. Five LULC categories were used, namely- urban area, mining area, vegetation, water bodies and other area (Rock outcrops and barren land). The LULC classified maps of two different periods i.e. 2018 and 1990 were generated on 1 : 50,000 scale. The accuracy assessment method was used to measure the accuracy of classified maps. This study shall be of good assistance to the town planners of Jodhpur city for the purpose of the sustainable development as per the master plan 2031

Engaging with sustainability issues in metropolitan Chennai : city report

Chennai is the largest metropolitan city in South India (8.7 million in 2011) and the provincial capital of the large state of Tamil Nadu (population 72 million in 2011). Before that, under British rule, the city was the capital of the Madras Presidency, and was known as Madras until 1996, when the name was officially changed to Chennai. Located on the east coast of India, on the Bay of Bengal, sea trade has been an important aspect of the regional economy since at least the colonial period. Still today, the city combines political functions with economic command functions for both manufacturing and services, reflecting the region's diversified economy. The Chennai metropolitan area has witnessed strong growth over the last 20 years in automobile manufacturing, software services, hardware manufacturing, healthcare and financial services (CDP 2009). However, it should be noted that only 30% of total employment in the city takes place in the formal sector i.e., is covered by contracts and labour laws, the remaining 70% falls in the informal sector. This underscores the importance of small and micro enterprises and self-employment for providing goods, services and livelihoods in the local economy

<i>Albugo candida</i> race diversity, ploidy and host-associated microbes revealed using DNA sequence capture on diseased plants in the field

• Physiological races of the oomycete Albugo candida are biotrophic pathogens of diverse plant species, primarily the Brassicaceae, and cause infections that suppress host immunity to other pathogens. However, A. candida race diversity and the consequences of host immunosuppression are poorly understood in the field. • We report a method that enables sequencing of DNA of plant pathogens and plant-associated microbes directly from field samples (Pathogen Enrichment Sequencing: PenSeq). We apply this method to explore race diversity in A. candida and to detect A. candida-associated microbes in the field (91 A. candida-infected plants).• We show with unprecedented resolution that each host plant species supports colonization by one of 17 distinct phylogenetic lineages, each with an unique repertoire of effector candidate alleles. These data reveal the crucial role of sexual and asexual reproduction, polyploidy and host domestication in A. candida specialization on distinct plant species. Our bait design also enabled phylogenetic assignment of DNA sequences from bacteria and fungi from plants in the field.• This paper shows that targeted sequencing has a great potential for the study of pathogen populations while they are colonizing their hosts. This method could be applied to other microbes, especially to those that cannot be cultured